BDBM649735 US20240043395, Compound 150::rac-3-fluoro-2-hydroxy-5-(2- (3-(pyrrolidin-1- yl)phenyl)morpholine-4- carbonyl)benzaldehyde

SMILES Oc1c(F)cc(cc1C=O)C(=O)N1CCOC(C1)c1cccc(c1)N1CCCC1

InChI Key InChIKey=OELKRUUQHVRRJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649735   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649735(rac-3-fluoro-2-hydroxy-5-(2- (3-(pyrrolidin-1- yl)...)
Affinity DataIC50: 7.50E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649735(rac-3-fluoro-2-hydroxy-5-(2- (3-(pyrrolidin-1- yl)...)
Affinity DataIC50: 3.10E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent