BDBM649721 3-fluoro-2-hydroxy-5-(1-(4- (trifluoromethyl)phenyl)-1H- pyrazol-4-yl)benzaldehyde::US20240043395, Compound 127

SMILES COc1cc(cc(F)c1O)-c1cnn(c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DZCYGXRMSXMTSC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 649721   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649721(3-fluoro-2-hydroxy-5-(1-(4- (trifluoromethyl)pheny...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649721(3-fluoro-2-hydroxy-5-(1-(4- (trifluoromethyl)pheny...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 9(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649721(3-fluoro-2-hydroxy-5-(1-(4- (trifluoromethyl)pheny...)
Affinity DataIC50: 100nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent