BDBM649698 N-(5-(4-cyclopropylpiperazin- 1-yl)thiazol-2-yl)-3-fluoro-5- formyl-4-hydroxybenzamide::US20240043395, Compound 5

SMILES Oc1c(F)cc(cc1C=O)C(=O)Nc1ncc(s1)N1CCN(CC1)C1CC1

InChI Key InChIKey=KLVMUDMVWJBFRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649698   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649698(N-(5-(4-cyclopropylpiperazin- 1-yl)thiazol-2-yl)-3...)
Affinity DataIC50: 5.30E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
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TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649698(N-(5-(4-cyclopropylpiperazin- 1-yl)thiazol-2-yl)-3...)
Affinity DataIC50: 2.70E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent