BDBM649695 3-fluoro-5-formyl-4-hydroxy- N-(5-phenyl-1,3,4-thiadiazol- 2-yl)benzamide::US20240043395, Compound 2

SMILES Oc1c(F)cc(cc1C=O)C(=O)Nc1nnc(s1)-c1ccccc1

InChI Key InChIKey=BAJDXSYSVGZFAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 649695   

TargetToll-like receptor 2(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649695(3-fluoro-5-formyl-4-hydroxy- N-(5-phenyl-1,3,4-thi...)
Affinity DataIC50: 6.70E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 6(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649695(3-fluoro-5-formyl-4-hydroxy- N-(5-phenyl-1,3,4-thi...)
Affinity DataIC50: 2.20E+3nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetToll-like receptor 9(Human)
Neuropore Therapies

US Patent
LigandPNGBDBM649695(3-fluoro-5-formyl-4-hydroxy- N-(5-phenyl-1,3,4-thi...)
Affinity DataIC50: 500nMAssay Description:On day 1, 50 μL of each test compound dilution in duplicates or a vehicle control was added to each well of a 96-well plate followed by addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent