BDBM649622 US11891403, Example 19

SMILES CN1C(=O)COc2ncn(Cc3nnn(C[C@H](O)c4ccc5cc(oc5c4)C#N)n3)c(=O)c12

InChI Key InChIKey=VGCAFBRCYYLAGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649622   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM649622(US11891403, Example 19)
Affinity DataIC50: 214nMAssay Description:The test compounds are dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
Go to US Patent