BDBM649608 (S)-(2,7-Dimethyl-3-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)- 2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)(6-fluoro-2- methylquinolin-4-yl)methanone::US11891387, Example 132

SMILES C[C@@H]1N(CCc2c1nn(C)c2-c1cc(n(C)n1)C(F)(F)F)C(=O)c1cc(C)nc2ccc(F)cc12

InChI Key InChIKey=YTTYSMSFSLFELF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 649608   

TargetMonoglyceride lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM649608((S)-(2,7-Dimethyl-3-(1-methyl-5-(trifluoromethyl)-...)
Affinity DataIC50: 27nMAssay Description:The assay used to measure the in vitro activity of MGL is adapted from the assay used for another serine hydrolase (FAAH) described in Wilson et al.,...More data for this Ligand-Target Pair
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Date in BDB:
4/8/2024
Entry Details
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