BDBM649222 N-{2-[4-(1,3-Benzothiazol-2-yl oxy)piperidin-1-yl]-2-[4-(difluoromethyl)-::US20240034737, Example 20
SMILES FC(F)c1ncsc1C(CNC(=O)c1c(F)cccc1Cl)N1CCC(CC1)Oc1nc2ccccc2s1
InChI Key InChIKey=GQLAKWIDZOLEQQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 649222
Affinity DataIC50: 17.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human P2X7 receptor expressed in HEK293 cells incubated for 5 mins followed by Bz-ATP addition measured after 3 mins by fluorescence ba...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of mouse P2X7 receptor expressed in HEK293 cells incubated for 5 mins followed by Bz-ATP addition measured after 3 mins by fluorescence ba...More data for this Ligand-Target Pair