BDBM648460 US20240033370, Hx No. CycBz-27

SMILES CCCN(OCCNC(=O)OC(C)C)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cnc(CN)nc1

InChI Key InChIKey=YVRFLFPVGAEDHM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 648460   

TargetToll-like receptor 7(Human)
Bolt Biotherapeutics

US Patent
LigandPNGBDBM648460(US20240033370, Hx No. CycBz-27)
Affinity DataEC50:  26nMAssay Description:HEK293 reporter cells expressing human TLR7 or human TLR8 were purchased from Invivogen and vendor protocols were followed for cellular propagation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Bolt Biotherapeutics

US Patent
LigandPNGBDBM648460(US20240033370, Hx No. CycBz-27)
Affinity DataEC50:  9nMAssay Description:HEK293 reporter cells expressing human TLR7 or human TLR8 were purchased from Invivogen and vendor protocols were followed for cellular propagation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent