BDBM648459 US20240033370, Hx No. CycBz-26

SMILES CCCN(CCCO)C(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cnc(CN)nc1

InChI Key InChIKey=XVMADMKWIFORGL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 648459   

TargetToll-like receptor 7(Human)
Bolt Biotherapeutics

US Patent
LigandPNGBDBM648459(US20240033370, Hx No. CycBz-26)
Affinity DataEC50:  9.00E+3nMAssay Description:HEK293 reporter cells expressing human TLR7 or human TLR8 were purchased from Invivogen and vendor protocols were followed for cellular propagation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Bolt Biotherapeutics

US Patent
LigandPNGBDBM648459(US20240033370, Hx No. CycBz-26)
Affinity DataEC50:  9.00E+3nMAssay Description:HEK293 reporter cells expressing human TLR7 or human TLR8 were purchased from Invivogen and vendor protocols were followed for cellular propagation a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent