BDBM648437 US20240033264, Example 3

SMILES CC(C)c1cnn2ccc(cc12)-c1ccnc(Nc2ccc(cn2)N2CC[C@@H](CC2=O)N(C)C)n1

InChI Key InChIKey=QZJWVFBTMGPBPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 648437   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM648437(US20240033264, Example 3)
Affinity DataIC50: 10nMAssay Description:The CDK4 enzyme assay for IC50 determination was performed as follows. Microfluidic kinase detection technology (Caliper) was used to monitor the pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM648437(US20240033264, Example 3)
Affinity DataIC50: 10nMAssay Description:The CDK6 enzyme assay for IC50 determination was performed as follows. Microfluidic kinase detection technology (Caliper) was used to monitor the pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Qilu Regor Therapeutics

US Patent
LigandPNGBDBM648437(US20240033264, Example 3)
Affinity DataIC50: 10nMAssay Description:The CDK2 enzyme assay for IC50 determination was performed as follows. Microfluidic kinase detection technology (Caliper) was used to monitor the pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent