BDBM648418 US11352350, Compound I-62

SMILES CN(CCCOCCCc1ccc2n(C3CCC(=O)NC3=O)c(=O)n(C)c2c1)C[C@H]1CC[C@@H](CC1)n1cc(NC(=O)c2coc(n2)-c2ccnc(NCC3CC3)c2)c(n1)C(F)F

InChI Key InChIKey=OBGPFASAQFREKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648418   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM648418(US11352350, Compound I-62)
Affinity DataIC50: 50nMAssay Description:Whole blood was collected in heparinized tubes and plated on the same day as draw (day 0). Whole blood was aliquoted into deep well plates. Compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2024
Entry Details
Go to US Patent