BDBM648159 US20240025922, Example 127

SMILES Cc1c2NCCOc2ncc1N1CCc2cnc(Nc3ccc(Cn4ccnc4)cc3)nc2C1

InChI Key InChIKey=ZIKCBDGNCSMKOR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648159   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Merck Patent

US Patent

LigandBDBM648159(US20240025922, Example 127)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2024
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL