BDBM647616 Synthesis of (R)-4-(3-methylmorpholine)-6-(1H-pyrazol-3-yl)-2,3-dihydropyrazolo[3,4-b]pyrrolo[2,3-d]pyridine-1(6H)-sulfonamide ::US20240025899, Compound 5

SMILES C[C@@H]1COCCN1c1nc2n(ncc2c2N(CCc12)S(N)(=O)=O)-c1cc[nH]n1

InChI Key InChIKey=LRMOFQNKZVIMHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647616   

TargetSerine/threonine-protein kinase ATR [14-953](Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM647616(US20240025899, Compound 5 | Synthesis of (R)-4-(3-...)
Affinity DataIC50: 6.5nMAssay Description:In this experiment, the phosphorylation level of substrate protein P53 (Eurofins, 14-952) was detected by HTRF technology to measure the activity of ...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent