BDBM646731 N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-2-yl]-6- (difluoromethyl)-1H-indole-3- sulfonamide::US20240025883, Example 236

SMILES COc1nc(NS(=O)(=O)c2c[nH]c3cc(ccc23)C(F)F)nc(OC)c1CC(F)F

InChI Key InChIKey=UFLZVYZRSLIPRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646731   

TargetUracil nucleotide/cysteinyl leukotriene receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM646731(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)
Affinity DataIC50: 14nMAssay Description:GPR17 cAMP Assay Protocol: CHO-K1 cells stably expressing vector containing untagged human GPR17 short isoform (Roche) were cultured at 37° C./5% CO2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
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