BDBM64651 MLS000714585::N-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)-thiophen-2-yl-methyl]propanamide::N-[(5-chloro-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]propanamide::N-[(5-chloro-8-hydroxy-7-quinolyl)-(2-thienyl)methyl]propionamide::N-[(5-chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide::SMR000274564::cid_3136134

SMILES CCC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O

InChI Key InChIKey=YTYAAHOPRAVKJV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 64651   

TargetRecBCD enzyme subunit RecD(Escherichia coli (strain K12))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64651(SMR000274564 | N-[(5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50: 1.19E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM64651(SMR000274564 | N-[(5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM64651(SMR000274564 | N-[(5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM64651(SMR000274564 | N-[(5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM64651(SMR000274564 | N-[(5-chloro-8-hydroxyquinolin-7-yl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-1 assessed as conjugated diene product formation using arachidonic acid by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed