BDBM646483 US11878973, Example 134

SMILES Oc1cccnc1C(=O)N1CCN(CC1)c1c(C2CC2)n(CC(=O)Nc2ccc(cc2)C(F)(F)F)c2nc(nn2c1=O)C1=CCOCC1

InChI Key InChIKey=IDXWQFIOMBACSC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646483   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Human)
Novartis

US Patent

LigandBDBM646483(US11878973, Example 134)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2024
Entry Details
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