BDBM646439 US11878973, Example 104

SMILES CCc1cc(C)c(NC(=O)Cn2c(CC)c(N3CCN(CC3)C(=O)c3ncccc3O)c(=O)n3nc(nc23)C2=CCOCC2)cc1Cl

InChI Key InChIKey=YTNBVJAFMLGTPU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646439   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Human)
Novartis

US Patent

LigandBDBM646439(US11878973, Example 104)Copy SMILESCopy InChI

Affinity DataIC50: 70nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2024
Entry Details
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