BDBM64627 2-N-(3,4-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-5-nitropyrimidine-2,4-diamine::MLS000588548::N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1-yl)-5-nitro-pyrimidine-2,4-diamine::N2-(3,4-dimethylphenyl)-6-(4-methyl-1-piperidinyl)-5-nitropyrimidine-2,4-diamine::N2-(3,4-dimethylphenyl)-6-(4-methylpiperidin-1-yl)-5-nitro-pyrimidine-2,4-diamine::SMR000219982::[4-amino-6-(4-methylpiperidino)-5-nitro-pyrimidin-2-yl]-(3,4-dimethylphenyl)amine::cid_3830492

SMILES CC1CCN(CC1)c1nc(Nc2ccc(C)c(C)c2)nc(N)c1[N+]([O-])=O

InChI Key InChIKey=IRZPWLOMSLYPHL-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 64627   

TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataIC50: 5.36E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataEC50:  6.15E+3nMAssay Description:Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, fluconazole, Hsp90, Calcineurin, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataEC50:  9.91E+3nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataEC50:  9.17E+3nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataIC50: 9.36E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM64627(N*2*-(3,4-Dimethyl-phenyl)-6-(4-methyl-piperidin-1...)
Affinity DataIC50: 5.36E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay