BDBM646255 1-((R)-2-(2-(5-((1R,2R,4S)-2-amino- 7-azabicyclo[2.2.1]heptane-7- carbonyl)-7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)pyrrolidin-1-yl)-2,2- dimethyl propan-1-one::US11878965, Example 246

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)[C@H]3CCCN3C(=O)C(C)(C)C)n(C)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646255   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646255(US11878965, Example 246 | 1-((R)-2-(2-(5-((1R,2R,4...)
Affinity DataIC50: 48.4nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2024
Entry Details
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