BDBM646239 (R)-N-((R)-1-(2-(5-((1S,4R,5R)-4- amino-2-azabicyclo[3.2.1]octane-2- carbonyl)-1-cyclopropyl-7-fluoro- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)ethyl)-2,2- difluorocyclopropane-1-carboxamide::US11878965, Example 227

SMILES C[C@@H](NC(=O)[C@H]1CC1(F)F)c1ccc2cc(-c3nc4cc(cc(F)c4n3C3CC3)C(=O)N3C[C@H](N)[C@@H]4CC[C@H]3C4)n(CC3CC3)c2n1

InChI Key InChIKey=YYQNLADCXBBSSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646239   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646239(US11878965, Example 227 | (R)-N-((R)-1-(2-(5-((1S,...)
Affinity DataIC50: 46.8nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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