BDBM646145 N-((R)-1-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1]heptane-7- carbonyl)-1-cyclopropyl-7-methoxy- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)ethyl)-3- fluorobicyclo[1.1.1]pentane-1- carboxamide::US11878965, Example 130

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)[C@@H](C)NC(=O)C34CC(F)(C3)C4)n(C3CC3)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646145   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646145(US11878965, Example 130 | N-((R)-1-(2-(5-((1R,2R,4...)
Affinity DataIC50: 45.1nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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