BDBM646118 ((1R,2R,4S)-2-amino-7- azabicyclo[2.2.1]heptan-7-yl) (2-(1-(cyclopropylmethyl)- 6-((S)-3-methyl- 1,1-dioxido-1,2-thiazinan-2- yl)-1H-pyrrolo[2,3-b]pyridin- 2-yl)-7- methoxy-1-methyl- 1H-benzo[d]imidazol-5- yl) methanone::US11878965, Example 103

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)N3[C@@H](C)CCCS3(=O)=O)n(C)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646118   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646118(US11878965, Example 103 | ((1R,2R,4S)-2-amino-7- a...)
Affinity DataIC50: 22.3nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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