BDBM646114 ((R)-3-aminopiperidin-1-yl)(1- cyclopropyl-2-(1- (cyclopropylmethyl)-6-((S)-3- methyl-1,1-dioxido-1,2- thiazinan-2-yl)-1H- pyrrolo[2,3-b]pyridin-2-yl)-1H- benzo[d]imidazol-5-yl) methanone::US11878965, Example 99

SMILES C[C@H]1CCCS(=O)(=O)N1c1ccc2cc(-c3nc4cc(ccc4n3C3CC3)C(=O)N3CCC[C@@H](N)C3)n(CC3CC3)c2n1

InChI Key InChIKey=CACDCDCFPDBQNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646114   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646114(US11878965, Example 99 | ((R)-3-aminopiperidin-1-y...)
Affinity DataIC50: 28.4nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
Go to US Patent