BDBM646113 ((1R,2R,4S)-2-amino-7- azabicyclo[2.2.1]heptan-7-yl) (1-cyclopropyl-2-(1- (cyclopropylmethyl)-6-((S)-3- methyl-1,1-dioxido-1,2- thiazinan-2-yl)-1H- pyrrolo[2,3-b]pyridin-2-yl)- 1H-benzo[d]imidazol-5- yl)methanone::US11878965, Example 98

SMILES C[C@H]1CCCS(=O)(=O)N1c1ccc2cc(-c3nc4cc(ccc4n3C3CC3)C(=O)N3[C@H]4CC[C@@H]3[C@H](N)C4)n(CC3CC3)c2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646113   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646113(US11878965, Example 98 | ((1R,2R,4S)-2-amino-7- az...)
Affinity DataIC50: 18.9nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2024
Entry Details
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