BDBM646094 N-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1] heptane-7-carbonyl)- 7-methoxy-1-methyl-1H- benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)-1H- pyrrolo[2,3-b]pyridin-6- yl)-N-methyl- methanesulfonamide::US11878965, Example 79

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)N(C)S(C)(=O)=O)n(C)c12)C(=O)N1[C@H]2CC[C@@H]1[C@H](N)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646094   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646094(US11878965, Example 79 | N-(2-(5-((1R,2R,4S)-2- am...)
Affinity DataIC50: 33.6nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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