BDBM646080 N-(2-(5-((1R,2R,4S)-2- amino-7-azabicyclo[2.2.1] heptane-7-carbonyl)- 1-cyclopropyl-1H-benzo[d] imidazol-2-yl)-1- (cyclopropylmethyl)-1H- pyrrolo[2,3-b] pyridin-6-yl)-N- (difluoromethyl) methanesulfonamide::US11878965, Example 65

SMILES CS(=O)(=O)N(C(F)F)c1ccc2cc(-c3nc4cc(ccc4n3C3CC3)C(=O)N3[C@H]4CC[C@@H]3[C@H](N)C4)n(CC3CC3)c2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646080   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646080(US11878965, Example 65 | N-(2-(5-((1R,2R,4S)-2- am...)
Affinity DataIC50: 47nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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