BDBM646071 N-(2-(5-((1R,2R,5R)-2-amino- 8-azabicyclo[3.2.1]octane-8- carbonyl)-1-cyclopropyl-1H- benzo[d]imidazol- 2-yl)-1-(cyclopropylmethyl)-1H- pyrrolo[2,3-b]pyridin-6-yl)-N- (difluoromethyl) methanesulfonamide::US11878965, Example 56

SMILES CS(=O)(=O)N(C(F)F)c1ccc2cc(-c3nc4cc(ccc4n3C3CC3)C(=O)N3[C@H]4CC[C@@H]3[C@H](N)CC4)n(CC3CC3)c2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646071   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646071(US11878965, Example 56 | N-(2-(5-((1R,2R,5R)-2-ami...)
Affinity DataIC50: 36.2nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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