BDBM646069 (R)-N-(2-(5-(3-aminopiperidine- 1-carbonyl)-1-cyclopropyl- 1H-benzo[d]imidazol-2-yl)-1- (cyclopropylmethyl)- 1H-pyrrolo[2,3- b]pyridin-6-yl)-N- (difluoromethyl) methanesulfonamide::US11878965, Example 54

SMILES CS(=O)(=O)N(C(F)F)c1ccc2cc(-c3nc4cc(ccc4n3C3CC3)C(=O)N3CCC[C@@H](N)C3)n(CC3CC3)c2n1

InChI Key InChIKey=TZYIHBPMTYBZIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646069   

TargetProtein-arginine deiminase type-4(Human)
Gilead Sciences

US Patent
LigandPNGBDBM646069(US11878965, Example 54 | (R)-N-(2-(5-(3-aminopiper...)
Affinity DataIC50: 37.4nMAssay Description:One hundred nanoliters of test compounds dissolved in DMSO at various concentrations were dispensed into a 384-well black OptiPlate using a Labcyte E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2024
Entry Details
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