BDBM645881 (R)-2-chloro-N-(2-((dimethyl(oxo)-λ6-sulfaneylidene)amino)-6-(trifluoromethyl)pyridin-4-yl)-8-methyl-8-(trifluoromethyl)-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[2,3-e]pyrimidine-6-carboxamide::US20240018157, Example 83

SMILES C[C@]1(CN(C(=O)Nc2cc(N=S(C)(C)=O)nc(c2)C(F)(F)F)c2cnc3cc(Cl)nn3c12)C(F)(F)F

InChI Key InChIKey=OHBUICQDUSWSGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645881   

LigandPNGBDBM645881(US20240018157, Example 83 | (R)-2-chloro-N-(2-((di...)
Affinity DataIC50: 10nMAssay Description:The final assay buffer includes 1 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
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