BDBM645837 US20240018157, Example 39

SMILES C[C@]1(CN(C(=O)Nc2cnc(c(Cl)c2)-n2nccn2)c2cnc3cc(F)nn3c12)C(F)(F)F

InChI Key InChIKey=DEMHKALZEXJNJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645837   

LigandPNGBDBM645837(US20240018157, Example 39)
Affinity DataIC50: 10nMAssay Description:The final assay buffer includes 2 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

LigandPNGBDBM645837(US20240018157, Example 39)
Affinity DataIC50: 10nMAssay Description:The final assay buffer includes 1 nM of MALT1 full-length protein, 50 μM Ac-LRSR-AMC substrate, 50 mM Tris pH 7.5, 600 mM Sodium Citrate, 1 mM D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent