BDBM645789 US20240018153, Compound I-28

SMILES CN(CCn1nc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12)C(=O)c1c(F)c(F)c(F)c(F)c1S(C)(=O)=O

InChI Key InChIKey=GHKWBWTZCAQJBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645789   

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645789(US20240018153, Compound I-28)
Affinity DataIC50: 10nMAssay Description:BMX Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM MnCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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TargetFibroblast growth factor receptor 4(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645789(US20240018153, Compound I-28)
Affinity DataIC50: 10nMAssay Description:FGFR4 Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM Mn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent