BDBM645787 US20240018153, Compound I-47

SMILES CN(C)S(=O)(=O)c1c(F)c(F)c(F)c(F)c1C(=O)NCCNc1ncnc2[nH]ccc12

InChI Key InChIKey=VDDNBCSMXCNGSH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645787   

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645787(US20240018153, Compound I-47)
Affinity DataIC50: 10nMAssay Description:BMX Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM MnCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645787(US20240018153, Compound I-47)
Affinity DataIC50: 10nMAssay Description:JAK3 Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM MnC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent