BDBM645764 US20240018153, Compound I-1

SMILES Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NS(=O)(=O)c4c(F)c(F)c(F)c(F)c4C(F)(F)F)cc23)cc1Cl

InChI Key InChIKey=BPIXHOJJXJCZMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645764   

TargetEpidermal growth factor receptor(Human)
2692372 Ontario

US Patent
LigandPNGBDBM645764(US20240018153, Compound I-1)
Affinity DataIC50: 10nMAssay Description:EGFR Kinase activity was monitored using a HTRF KinEASE-TK kit from Cisbio (62TK0PEC). The buffer used was 1 kinase buffer supplemented with 2 mM MnC...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
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