BDBM64576 (3Z)-5-ethyl-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-1H-indol-2-one::(3Z)-5-ethyl-3-(2-oxo-2-thiophen-2-ylethylidene)-1H-indol-2-one::(3Z)-5-ethyl-3-[2-keto-2-(2-thienyl)ethylidene]oxindole::5-ethyl-3-[2-oxo-2-(2-thienyl)ethylidene]-1,3-dihydro-2H-indol-2-one::MLS000536892::SMR000143539::cid_977927

SMILES CCc1ccc2NC(=O)\C(=C/C(=O)c3cccs3)c2c1

InChI Key InChIKey=ITYGMUOLJUBSJY-UHFFFAOYSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 64576   

Target60S ribosomal protein L19-A(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataEC50:  4.42E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetVacuolar aminopeptidase 1(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataEC50:  4.07E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetATP-dependent molecular chaperone HSP82(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataEC50:  2.91E+3nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein phosphatase(Yeast)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataEC50:  5.99E+3nMAssay Description:Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetNeurotensin receptor type 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataEC50:  1.77E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataIC50: 4.97E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64576(cid_977927 | SMR000143539 | MLS000536892 | (3Z)-5-...)
Affinity DataIC50: 4.53E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay