BDBM645744 US20240018151, Example 1::US20240018151, Example 17

SMILES Cc1cccc(c1)-c1ccn(n1)-c1cc(N2CCOCC2)n2nc(cc2n1)-c1ccncc1

InChI Key InChIKey=YTPKWXFUHGVDSO-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645744   

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Tme Therapeutics

US Patent
LigandPNGBDBM645744(US20240018151, Example 17 | US20240018151, Example...)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Tme Therapeutics

US Patent
LigandPNGBDBM645744(US20240018151, Example 17 | US20240018151, Example...)
Affinity DataIC50: 50nMAssay Description:Briefly, 4 compound solution and 4 ATP solution are prepared with assay buffer (50 mM MOPS, 1 mM DTT, pH7.2). 4 Substrate solution and 4 kinase/Metal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Tme Therapeutics

US Patent
LigandPNGBDBM645744(US20240018151, Example 17 | US20240018151, Example...)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent