BDBM645719 (6-chloro-8-(2-(2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridin-2-yl)((1R,5R)-6- (hydroxymethyl)-3- azabicyclo[3.1.0]hexan-3- yl)methanone::US20240018140, Compound 60

SMILES OCC1[C@@H]2CN(C[C@@H]12)C(=O)c1cn2cc(Cl)cc(-c3ccccc3OCC(F)(F)F)c2n1

InChI Key InChIKey=PNZMIANZPZJVFQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645719   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645719(US20240018140, Compound 60 | (6-chloro-8-(2-(2,2,2...)
Affinity DataEC50:  30nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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