BDBM645708 (2-methyl-5-oxa-2,8- diazaspiro[3.5]nonan-8-yl)(8-(2- (2,2,2- trifluoroethoxy)phenyl)imidazo[1,2- a]pyridin-2-yl)methanone::US20240018140, Compound 49

SMILES CN1CC2(C1)CN(CCO2)C(=O)c1cn2cccc(-c3ccccc3OCC(F)(F)F)c2n1

InChI Key InChIKey=CYRAGTHPGMHLOZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645708   

TargetCeramide glucosyltransferase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM645708(US20240018140, Compound 49 | (2-methyl-5-oxa-2,8- ...)
Affinity DataEC50:  18nMAssay Description:Using Promega's UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
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