BDBM645443 2-[4-(2-aminoethyl)piperazin- 1-yl]-N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2- yl)acetamide::US20240018122, Example 108

SMILES Cc1nnc(cc1Nc1ccnc(NC(=O)CN2CCN(CCN)CC2)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=BSOPXKNEXJLZSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645443   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645443(US20240018122, Example 108 | 2-[4-(2-aminoethyl)pi...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645443(US20240018122, Example 108 | 2-[4-(2-aminoethyl)pi...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent