BDBM645440 US20240018122, Example 105::methyl N-[2-(4-{2-[(4-{[6-(5- chloro-2-fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2- yl)carbamoyl]ethyl} piperazin-1-yl)ethyl]-N- methylcarbamate

SMILES COC(=O)N(C)CCN1CCN(CCC(=O)Nc2cc(Nc3cc(nnc3C)-c3cc(Cl)ccc3F)ccn2)CC1

InChI Key InChIKey=FOTWITILHFGMSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645440   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645440(US20240018122, Example 105 | methyl N-[2-(4-{2-[(4...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645440(US20240018122, Example 105 | methyl N-[2-(4-{2-[(4...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent