BDBM645430 N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2-yl)-3-{[2- (methylamino)ethyl]amino} propanamide::US20240018122, Example 93

SMILES CNCCNCCC(=O)Nc1cc(Nc2cc(nnc2C)-c2cc(Cl)ccc2F)ccn1

InChI Key InChIKey=LAPOSPCQIMEYHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645430   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645430(US20240018122, Example 93 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645430(US20240018122, Example 93 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent