BDBM645429 4-(3-((4-((6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl)amino)pyridin-2- yl)amino)-3- oxopropyl)piperazine-2- carboxylic acid::US20240018122, Example 92

SMILES Cc1nnc(cc1Nc1ccnc(NC(=O)CCN2CCNC(C2)C(O)=O)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=ZDJOXEPJIISEQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645429   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645429(US20240018122, Example 92 | 4-(3-((4-((6-(5-chloro...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645429(US20240018122, Example 92 | 4-(3-((4-((6-(5-chloro...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent