BDBM645425 N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2-yl)-3-[4- (2- methanesulfonylethyl) piperazin-1-yl]propanamide::US20240018122, Example 83

SMILES Cc1nnc(cc1Nc1ccnc(NC(=O)CCN2CCN(CCS(C)(=O)=O)CC2)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=MCVUETVZZHMMKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645425   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645425(US20240018122, Example 83 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
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