BDBM645421 N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2-yl)-3- (morpholin-4-yl)propanamide::US20240018122, Example 78

SMILES Cc1nnc(cc1Nc1ccnc(NC(=O)CCN2CCOCC2)c1)-c1cc(Cl)ccc1F

InChI Key InChIKey=DCQLIAKYVAASIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645421   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645421(US20240018122, Example 78 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent