BDBM645418 N-(4-{[6-(5-chloro-2- fluorophenyl)-3- methylpyridazin-4- yl]amino}pyridin-2-yl)-4-(4- methylpiperazin-1- yl)butanamide::US20240018122, Example 65

SMILES CN1CCN(CCCC(=O)Nc2cc(Nc3cc(nnc3C)-c3cc(Cl)ccc3F)ccn2)CC1

InChI Key InChIKey=VYVMPWVQVKJSCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645418   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645418(US20240018122, Example 65 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2024
Entry Details
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