BDBM645417 N-(4-{[6-(5-chloro-2- fluorophenyl)pyridazin-4- yl]amino}pyridin-2-yl)-3-(3- methanesulfonyl-1,3- diazinan-1-yl)propanamide::US20240018122, Example 44

SMILES CS(=O)(=O)N1CCCN(CCC(=O)Nc2cc(Nc3cnnc(c3)-c3cc(Cl)ccc3F)ccn2)C1

InChI Key InChIKey=AWSNZPSGEKSQFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 645417   

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM645417(US20240018122, Example 44 | N-(4-{[6-(5-chloro-2- ...)
Affinity DataIC50: 1nMAssay Description:The enzymatic activity of compounds of the present invention was monitored measuring the formation of ADP using the ADP-GLO Kinases assay. Following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent