BDBM645409 US20240016810, Compound TABLE 16.22::US20240150358, Example 00188::US20240208964, Biochemistry 22

SMILES C1CN(CCO1)c1cc(nc2nc(nn12)-c1ccncc1)-n1nccc1-c1ccccc1

InChI Key InChIKey=AUWHACZNKAOEHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645409   

LigandPNGBDBM645409(US20240016810, Compound TABLE 16.22 | US2024020896...)
Affinity DataIC50: 767nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645409(US20240016810, Compound TABLE 16.22 | US2024020896...)
Affinity DataIC50: 767nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645409(US20240016810, Compound TABLE 16.22 | US2024020896...)
Affinity DataIC50: 767nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent