BDBM645407 US20240016810, Compound TABLE 16.20::US20240150358, Example 00186::US20240208964, Biochemistry 20::US20250145642, Compound LastTbl.20::US20250197375, Compound Fig.7.20

SMILES C(Oc1nc(nc2N(CCc12)c1ccccc1)N1CCOCC1)c1cccnc1

InChI Key InChIKey=WZVWOMFCMAGUMP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 645407   

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

LigandPNGBDBM645407(US20240016810, Compound TABLE 16.20 | US2024020896...)
Affinity DataIC50: 2.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent