BDBM645388 US11873304, Example 23

SMILES N\N=C(/N=N)C1CCN(Cc2cccc(F)c2Cc2nc3cc(nc(N)n3n2)-c2cccc(C#N)c2F)C1

InChI Key InChIKey=UURBMIFYOCRIQL-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 645388   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM645388(US11873304, Example 23)
Affinity DataEC50:  55nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM645388(US11873304, Example 23)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent