BDBM645384 Trans-(5-(2-(piperidin-4-ylmethylamino) cyclopropyl)indolin-1-yl)(3- (trifluoromethyl)phenyl)methanone::US11873292, Compound A48

SMILES FC(F)(F)c1cccc(c1)C(=O)N1CCc2cc(ccc12)C1CC1NCC1CCNCC1

InChI Key InChIKey=CGDURJBMPOUUBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645384   

TargetLysine-specific histone demethylase 1A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645384(Trans-(5-(2-(piperidin-4-ylmethylamino) cyclopropy...)
Affinity DataIC50: 25.6nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645384(Trans-(5-(2-(piperidin-4-ylmethylamino) cyclopropy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM645384(Trans-(5-(2-(piperidin-4-ylmethylamino) cyclopropy...)
Affinity DataIC50: 4.26E+4nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
Go to US Patent