BDBM645377 US20240016810, Compound TABLE 15.2::US20240150358, Example 00167::US20240208964, Biochemistry b2

SMILES Cc1cccc(\C=N\Nc2cc(N3CC4CC3CO4)n3nc(cc3n2)-c2ccncc2)c1

InChI Key InChIKey=IVWSQFBMXFUYBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 645377   

LigandPNGBDBM645377(US20240016810, Compound TABLE 15.2 | US20240208964...)
Affinity DataIC50: 12nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645377(US20240016810, Compound TABLE 15.2 | US20240208964...)
Affinity DataIC50: 12nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Kineta

US Patent
LigandPNGBDBM645377(US20240016810, Compound TABLE 15.2 | US20240208964...)
Affinity DataIC50: 3nMAssay Description:The biochemical PIKFyve inhibition assays were run by Carna Biosciences according to proprietary methodology based on the Promega ADP-Glo Kinase assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent